Test Services

Preservative Effectiveness Testing

BACKGROUND
When preservatives are used for the purpose of minimizing growth of microorganisms, the effectiveness of the preservative within the context of the compounds formulation will need to be validated. There are standard organisms used for this test, however it is always good practice (but not required) to test the effectiveness of the preservative against organisms isolated from the facility in which the product is compounded. Validation that the preservative is effective should include out to and including the beyond use date.

OUR METHODOLOGY
DYNALABS method for antimicrobial effectiveness testing is based on the standards delineated in USP <51>. DYNALABS will perform this test using customer supplied material, or will compound and test material based on the customer supplied formulation. The standard organisms called out for in USP <51> will be supplied by DYNALABS, and DYNALABS will work with the customer to help in isolating and growing up organisms resident within the compounding facility.

FORMS TYPICALLY TESTED

• All forms of medications with preservatives.